{"id":9021,"date":"2018-08-20T08:00:50","date_gmt":"2018-08-20T06:00:50","guid":{"rendered":"https:\/\/zdravovek.eu\/?p=9021"},"modified":"2020-09-15T13:32:24","modified_gmt":"2020-09-15T11:32:24","slug":"histamin-deprese","status":"publish","type":"post","link":"https:\/\/zdravovek.eu\/cs\/histamin-deprese\/","title":{"rendered":"Vysok\u00e1 hladina histaminu &#8211; m\u016f\u017ee zp\u016fsobit depresi?"},"content":{"rendered":"<p>O ne\u017e\u00e1douc\u00edch \u00fa\u010dinc\u00edch histaminu jsme si u\u017e n\u011bco to popsali v s\u00e9rii o <a href=\"https:\/\/zdravovek.eu\/histaminova-intolerancia\/\" rel=\"noopener\">histaminov\u00e9 intoleranci<\/a>.<\/p>\n<p>Histamin ma <strong>mnoho \u00fa\u010dink\u016f na na\u0161e fyzick\u00e9 t\u011blo<\/strong> a v\u011bt\u0161ina autor\u016f se v\u011bnuje pr\u00e1v\u011b t\u00e9to sf\u00e9\u0159e.<\/p>\n<p>Ale my se v tomto \u010dl\u00e1nku pod\u00edv\u00e1me na vliv histaminu na na\u0161e <strong>du\u0161evn\u00ed zdrav\u00ed<\/strong> &#8211; konkr\u00e9tn\u011b jeho \u00fa\u010dinky <strong>na vznik deprese<\/strong>.<\/p>\n\n<h2>Histamin a deprese<\/h2>\n<p>Americk\u00fd farmakolog Pfeiffer byl prvn\u00ed, kter\u00fd zkoumal <strong>souvislost mezi histaminem a depres\u00ed<\/strong>. Ve velk\u00e9 studii se p\u0159i\u0161lo na to, \u017ee zv\u00fd\u0161en\u00e9 hladiny histaminu <strong>zvy\u0161uj\u00ed riziko vzniku deprese<\/strong>.<\/p>\n<p>P\u016fvod takov\u00e9 deprese nen\u00ed stejn\u00fd jako p\u0159i klasick\u00e9 depresi (kde nap\u0159\u00edklad doch\u00e1z\u00ed k nerovnov\u00e1ze mezi serotoninem p\u0159\u00edpadn\u011b dopaminem). Z toho vypl\u00fdv\u00e1, \u017ee deprese na podklad\u011b histaminu <strong>nebude reagovat na klasick\u00e1 antidepresiva<\/strong>.<\/p>\n<p>Mnoho pacient\u016f s histaminovou intoleranc\u00ed se \u010dasto c\u00edt\u00ed depresivn\u011b. Ne v\u0161ichni si v\u0161ak uv\u011bdom\u00ed, \u017ee deprese je <strong>zp\u016fsobena<\/strong> pr\u00e1v\u011b <strong>nadbytkem histaminu<\/strong> v t\u011ble. I proto se pomalu za\u010d\u00ednaj\u00ed pou\u017e\u00edvat antihistaminika k l\u00e9\u010db\u011b n\u011bkter\u00fdch du\u0161evn\u00edch onemocn\u011bn\u00ed.<\/p>\n<h2>Z\u00e1n\u011bt a jeho negativn\u00ed dopad<\/h2>\n<p>Angli\u010dt\u00ed v\u011bdci tyto teorie potvrzuj\u00ed.<\/p>\n<p>Zjistili toti\u017e, \u017ee existuje v\u00fdznamn\u00e1 souvislost mezi z\u00e1n\u011btliv\u00fdmi onemocn\u011bn\u00edmi a depres\u00ed. Z\u00e1n\u011bt je <strong>obrann\u00fd mechanismus t\u011bla<\/strong>, p\u0159i kter\u00e9m <strong>nar\u016fst\u00e1 koncentrace<\/strong> z\u00e1n\u011btliv\u00fdch parametr\u016f (nap\u0159\u00edklad C-reaktivn\u00ed protein &#8211; CRP) ale i z\u00e1n\u011btliv\u00fdch neuromedi\u00e1tor\u016f &#8211; nap\u0159\u00edklad <strong>histamin<\/strong>\u00a0a imunitn\u00ed slo\u017eky &#8211; <strong>cytokiny<\/strong> (Psychopharm-2011).<\/p>\n<p>Vznik z\u00e1n\u011btu dok\u00e1\u017ee ovlivnit stres, ale i \u0161patn\u00e9 stravov\u00e1n\u00ed. Infekce v d\u011btsk\u00e9m v\u011bku a z\u00e1va\u017en\u011bj\u0161\u00ed poran\u011bn\u00ed tak\u00e9 ovlivn\u00ed imunitn\u00ed syst\u00e9m. V\u0161echny tyto faktory se zapisuj\u00ed a v pozd\u011bj\u0161\u00edm v\u011bku se mohou projevit jako r\u016fzn\u00e1\u00a0<strong>imunitn\u00ed onemocn\u011bn\u00ed<\/strong>.<\/p>\n<p>Pacienti, kte\u0159\u00ed byli l\u00e9\u010deni <strong>l\u00e9ky<\/strong>, kter\u00e9 mohou vyvolat z\u00e1n\u011bt (nap\u0159\u00edklad interferon pro l\u00e9\u010dbu virov\u00e9 hepatitidy, ale i jin\u00fdch onemocn\u011bn\u00ed) jsou <strong>n\u00e1chyln\u011bj\u0161\u00ed na deprese<\/strong>. Naopak, depresivn\u00ed pacienti sou\u010dasn\u011b <strong>l\u00e9\u010deni protiz\u00e1n\u011btliv\u00fdmi l\u00e1tk\u00e1mi<\/strong>\u00a0(nap\u0159\u00edklad p\u0159i artritid\u011b) poci\u0165ovali <strong>zlep\u0161en\u00ed p\u0159\u00edznak\u016f deprese<\/strong>.<\/p>\n<p>V sou\u010dasnosti prob\u00edh\u00e1 n\u011bkolik studi\u00ed na pacientech, kte\u0159\u00ed nereagovali na klasick\u00e1 antidepresiva a hledaj\u00ed se nov\u00e9 zp\u016fsoby jejich l\u00e9\u010dby [1]. V\u00fdhodn\u00e1 se ukazuje <strong>protiz\u00e1n\u011btliv\u00e1 l\u00e9\u010dba deprese<\/strong>.<\/p>\n<div class=\"erit-block erit-block-tip\">\n<p>Chcete zjistit, kter\u00e9 jsou nejlep\u0161\u00ed protiz\u00e1n\u011btliv\u00e9 potraviny? Tyto pat\u0159\u00ed mezi <strong><a href=\"https:\/\/zdravovek.eu\/top-15-protizapalovych-jedal\/\">top 15 potravin<\/a> <\/strong> proti z\u00e1n\u011btu a m\u011bli byste je j\u00edst pravideln\u011b.<\/p>\n<\/div>\n<h2>P\u0159\u00edznaky nadbytku histaminu<\/h2>\n<p>Odborn\u011b se tento term\u00edn naz\u00fdv\u00e1 <strong>histadelie<\/strong>.<\/p>\n<p>Jak tedy zjist\u00edte, \u017ee m\u016f\u017eete m\u00edt nadbyte\u010dn\u00e9 hladiny neurotransmiteru histaminu?<\/p>\n<ul>\n<li>Onemocn\u011bn\u00ed se projev\u00ed kolem <strong>20. roku <\/strong> <strong>\u017eivota<\/strong>.<\/li>\n<li>Na jeho vznik m\u00e1 v\u00fdrazn\u00fd vliv <strong>genetika<\/strong>. Proto pokud se vyskytlo ve va\u0161\u00ed rodin\u011b, jsou \u0161ance vy\u0161\u0161\u00ed i u v\u00e1s.<\/li>\n<li>Pacienti s nadbyte\u010dn\u00fdm histaminem jsou v\u011bt\u0161inou <strong>\u0161t\u00edhl\u00e9 postavy<\/strong>, proto\u017ee maj\u00ed zrychlen\u00fd metabolismus.<\/li>\n<li>\u010cast\u00e1 je <strong>zv\u00fd\u0161en\u00e1 produkce slin<\/strong> a hlenu.<\/li>\n<li>P\u0159\u00edtomny jsou i <strong>zm\u011bny chov\u00e1n\u00ed<\/strong>, nep\u0159edv\u00eddateln\u00e9, nutkav\u00e9 jedn\u00e1n\u00ed, hyperaktivita.<\/li>\n<li><strong>Depresivn\u00ed n\u00e1lady<\/strong>, poruchy sp\u00e1nku a lehk\u00e1 sexu\u00e1ln\u00ed vzru\u0161ivost.<\/li>\n<li>Pacienti maj\u00ed \u0159\u00eddk\u00e9 vlasy a redukovan\u00e9 ochlupen\u00ed.<\/li>\n<\/ul>\n<div class=\"erit-block erit-block-interesting\">\n<p>Jen pro zaj\u00edmavost, p\u0159ibli\u017en\u011b <strong>20 % schizofrenn\u00edch pacient\u016f<\/strong> p\u0159edstavuje skupina histadelik\u016f, tvrd\u00ed kanadsk\u00fd psychiatr Abram Hoffer.<\/p>\n<\/div>\n<h2>L\u00e9\u010dba histaminov\u00e9 deprese<\/h2>\n<div class='erit-product-small-box erit-float-right '>\n                <div class='erit-product-small-box-header'>\n                  <div class='erit-product-small-box-name'>\n                   <a href='https:\/\/zdravovek.eu\/a\/cs\/daosin-30-tobolek-pilulka-cz\/' class='eap_conversion product_small_box product_name' rel='nofollow' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_product_small_box', 'EAP_click_product_name', null)\">DAOSIN<\/a>\n                  <\/div>\n                  <div class='erit-product-small-box-desc'>30 tobolek<\/div>\n                <\/div>\n\n                <div class='erit-product-small-box-row-wrap'>\n                  <div class='erit-product-small-box-img_wrap'>\n                    <a href='https:\/\/zdravovek.eu\/a\/cs\/daosin-30-tobolek-pilulka-cz\/' class='eap_conversion product_small_box image' rel='nofollow' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_product_small_box', 'EAP_click_image', null)\">\n                      <img width='150' src='https:\/\/zdravovek.eu\/wp-content\/uploads\/2018\/03\/daosin.png' alt='DAOSIN'\/>\n                    <\/a>\n                  <\/div>\n\n                  <div class='erit-product-small-box-right-wrap'>\n                   <div class='erit-product-small-box-buttons'><a class='erit-product-small-box-shop-button eap_conversion product_small_box cta_button ' href='https:\/\/zdravovek.eu\/a\/cs\/daosin-30-tobolek-pilulka-cz\/' rel='nofollow noopener' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_product_small_box', 'EAP_click_cta_button', null)\">\n                          Do obchodu\n                      <\/a>\n                    <\/div>\n                    <div class='erit-product-small-box-price'>\n                      699&nbsp;K\u010d\n                    <\/div>\n                    <div class='erit-product-small-box-free-shipping '>\n                      Doprava zdarma\n                    <\/div>\n                  <\/div>\n                <\/div>\n              <\/div>Pokud m\u00e1te podez\u0159en\u00ed, \u017ee vysok\u00e9 hladiny histaminu by mohly u v\u00e1s <strong>zp\u016fsobovat depresi<\/strong>, pora\u010fte se se sv\u00fdm praktick\u00fdm l\u00e9ka\u0159em. Ten v\u00e1m doporu\u010d\u00ed vhodn\u00fd postup.<\/p>\n<ul>\n<li>V l\u00e9\u010db\u011b je vysoce \u00fa\u010dinn\u00fd <strong><a href='https:\/\/zdravovek.eu\/a\/cs\/phyteneo-methionin-komplex-60-kapsli-drmax-cz\/' class='eap_conversion affil_link' rel='nofollow noopener' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_affil_link_a', 'EAP_click_affil_link_a', null)\">methionin<\/a><\/strong>, kter\u00fd se d\u00e1 koupit v komplexu vitam\u00edn\u016f a miner\u00e1l\u016f ve v\u00fd\u017eivov\u00e9m dopl\u0148ku i bez p\u0159edpisu. Methionin je aminokyselina, kter\u00e1 dok\u00e1\u017ee odbour\u00e1vat histamin t\u00edm, \u017ee doch\u00e1z\u00ed k jeho methylaci.<\/li>\n<li>Efektivn\u00ed je i oby\u010dejn\u00e9 <strong><a href='https:\/\/zdravovek.eu\/a\/cs\/biomin-calcium-neo-s-vitamin-d-90-kapsli-pilulka-cz\/' class='eap_conversion affil_link' rel='nofollow noopener' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_affil_link_a', 'EAP_click_affil_link_a', null)\">kalcium<\/a><\/strong>. L\u00e9ka\u0159 v\u0161ak m\u016f\u017ee zvolit i l\u00e9\u010dbu <strong>antihistaminiky p\u0159\u00edpadn\u011b antidepresivem<\/strong> se specifick\u00fdm \u00fa\u010dinkem.<\/li>\n<li>Pacient\u016fm s HIT doporu\u010dujeme i dopl\u0148ov\u00e1n\u00ed chyb\u011bj\u00edc\u00edho enzymu DAO (<strong><a href='https:\/\/zdravovek.eu\/a\/cs\/daosin-30-tobolek-pilulka-cz\/' class='eap_conversion affil_link' rel='nofollow noopener' target='_blank'  onclick=\"eap_add_gtm_event('EAP_conversion_affil_link_a', 'EAP_click_affil_link_a', null)\">p\u0159\u00edpravek Daosin<\/a><\/strong>). P\u0159e\u010dt\u011bte si v\u00edce o DAO a jeho \u00fa\u010dinc\u00edch <a href=\"https:\/\/zdravovek.eu\/daosin\/\">v t\u00e9to recenzi<\/a>.<\/li>\n<\/ul>\n<p>Tak jako u v\u0161ech onemocn\u011bn\u00ed s nadbytkem histaminu, d\u016fle\u017eit\u00e9 je i <strong>kvalitn\u00ed stravov\u00e1n\u00ed<\/strong>. Vyh\u00fdbejte se histaminem nabit\u00fdm potravin\u00e1m a jezte jen <strong>\u010derstv\u00e9 potraviny<\/strong> a \u010derstv\u011b p\u0159ipraven\u00e1 j\u00eddla.<\/p>\n<h2>Z\u00e1v\u011br<\/h2>\n<p>Deprese je onemocn\u011bn\u00ed, o kter\u00e9m se st\u00e1le mnoho lid\u00ed styd\u00ed mluvit. N\u00e1v\u0161t\u011bvu psychiatra mnoz\u00ed odkl\u00e1daj\u00ed, a kdy\u017e se k n\u011bmu u\u017e doberou, styd\u00ed se za to. Depka, jak se toto onemocn\u011bn\u00ed naz\u00fdv\u00e1 lidov\u011b, m\u00e1 mnoho p\u0159\u00ed\u010din. Jednou z nich m\u016f\u017ee b\u00fdt i <strong>nadbytek histaminu<\/strong>.<\/p>\n<p>Pokud jste pacient s HIT nebo <strong>m\u00e1te zv\u00fd\u0161en\u00e9 hladiny histaminu<\/strong> z jin\u00e9ho d\u016fvodu, dbejte o sv\u00e9 du\u0161evn\u00ed zdrav\u00ed a v p\u0159\u00edpad\u011b n\u00e1v\u0161t\u011bvy psychiatra ho informujte o va\u0161\u00ed HIT. M\u016f\u017eete mu tak <strong>usnadnit zp\u016fsob l\u00e9\u010dby<\/strong> a zkr\u00e1tit jej\u00ed \u010das.<\/p>\n<div class=\"erit-block erit-block-tip\">\n<p>Jedn\u00edm ze z\u00e1kladn\u00edch krok\u016f, jak zv\u00edt\u011bzit nad histaminem, je dobr\u00e1 strava. Pokud ani ta nepom\u016f\u017ee, m\u016f\u017eete si pomoci n\u011bkter\u00fdmi l\u00e9ky. Kter\u00e9 jsou <strong>nejlep\u0161\u00ed l\u00e9ky a dopl\u0148ky v\u00fd\u017eivy<\/strong> p\u0159i HIT\u00a0<a href=\"https:\/\/zdravovek.eu\/histaminova-intolerancia-lieky\/\">zjist\u00edte v tomto \u010dl\u00e1nku<\/a>.<\/p>\n<\/div>\n<p><strong>Zdroje<\/strong>:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.livestrong.com\/article\/490504-high-histamines-depression\/\" target=\"_blank\" rel=\"noopener noreferrer\">livestrong.com<\/a><\/li>\n<li><a href=\"https:\/\/healinghistamine.com\/researcher-finds-depression-is-caused-by-histamine-inflammation\/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">healinghistamine.com<\/a><\/li>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5050394\/\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">[1]<\/a> Studie o protiz\u00e1n\u011btliv\u00e9 l\u00e9\u010db\u011b deprese<\/li>\n<\/ul>\n<div class='erit-disclaimer'><span class='erit-disclaimer-icon'><span class='erit-disclaimer-text'>!<\/span><\/span><span class='erit-disclaimer-text'>\u010cl\u00e1nek byl vypracov\u00e1n l\u00e9k\u00e1rn\u00edkem av\u0161ak, slou\u017e\u00ed pouze pro informativn\u00ed \u00fa\u010dely - nenahrazuje l\u00e9ka\u0159sk\u00e9 vy\u0161et\u0159en\u00ed, nebo osobn\u00ed setk\u00e1n\u00ed v l\u00e9k\u00e1rn\u011b.<\/span><\/div>\n<script type='text\/javascript' >\n                jQuery(document).ready(function($) {\n    \n                    let data = {\n                        'action': 'render_widget_action',\n                        'postId': null,\n                        'categoryId': null\n                    };\n    \n                    let ajaxUrlFromPHP = 'https:\/\/zdravovek.eu\/wp-admin\/admin-ajax.php';\n                    jQuery.post(ajaxUrlFromPHP, data, function(response) {\n                        if(response == 0){\n                            \/\/ chyba\n                            jQuery( '#eap_top_w' ).html( '' );\n                            jQuery( '#eap_top_w_wrap' ).hide();\n                        } if(response == -1){\n                            \/\/ nenasli ziadne produkty\n                            jQuery( '#eap_top_w' ).html( '' );\n                            jQuery( '#eap_top_w_wrap' ).hide();\n                        } else {\n                            let desktop = $(window).width() > 960;\n                            if(desktop){\n                                jQuery( '#eap_top_w' ).html( response );\n                                jQuery( '#eap_top_w_wrap' ).fadeIn(1000);\n                            } else {\n                                jQuery( '#eap_top_w_mob_chart' ).html( response );\n                                jQuery( '#eap_top_w_mob' ).fadeIn(1000); 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Histamin ma mnoho \u00fa\u010dink\u016f na na\u0161e fyzick\u00e9 t\u011blo a v\u011bt\u0161ina autor\u016f se v\u011bnuje pr\u00e1v\u011b t\u00e9to sf\u00e9\u0159e. Ale my se v tomto \u010dl\u00e1nku pod\u00edv\u00e1me na vliv histaminu na na\u0161e du\u0161evn\u00ed zdrav\u00ed &#8211; konkr\u00e9tn\u011b jeho \u00fa\u010dinky na vznik deprese. Histamin a deprese [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":10435,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[81,79],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v15.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Vysok\u00e1 hladina histaminu - m\u016f\u017ee zp\u016fsobit depresi? | Zdravov\u011bk<\/title>\n<meta name=\"description\" content=\"M\u00e1 deprese souvislost s hladinou histaminu v na\u0161em t\u011ble? 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